Synthesis and characterization of new metal-free and metal-substituted phthalocyanine compounds and study Molecular docking
Hussein Ali Al-Bahrani
Department of Chemistry. College of Education for Pure Science, University of Kerbala Iraq
Keywords: Nickel phthalocyanine, Cobalt phthalocyanine, metal-free phthalocyanine
Abstract
A newly of cobalt and nickel derivative of phthlocyanine were synthesized. Tetra nitro cobalt phthalocyanine, tetra-(5-amino-2-hydroxybenzoic) cobalt phthalocyanine were synthesized and recrystalized. By adding 5-aminosalicylic acid, tetra-(5-amino salicylic acid) Cobalt phthalocyanine was synthesized. Nickel derivatives were synthesized via the same pattern. Phthalocyanine without metal is synthesized also. All the derivatives were separated, recrystallized and identified using FTIR, 1H NMR, and UV spectroscopy. The molecular docking study was addressed in this work and reviled a promising biological activities especialy the compound with molecule not containing metal element.
References
Kieran. N, Synthesis of Novel Red- Shifted Phthalocyanines, Ph.D Thesis, chemical science
dullin city Univercity, (2006),1-11.
Mikhalenko S.A, Barknova S.V, Lebede. V, and E. A. Luk yanets. Synthesis and electronic
absorption spectra of tetra-4-tert-butylphthalocyanines, (1971),41,2735.
Practical Applications of Phthalocyanines – from Dyes and Pigments to Materials for Optical,
Electronic and Photo-electronic Devices Dieter Wöhrle,a@ Günter Schnurpfeil,a Sergey G.
Makarov,b Alexander Kazarin,b and Olga N. SuvorovabMacroheterocycles 2012 5(3) 191-
, doi: 10.6060/mhc2012.120990w
Turk J Chem. 2020; 44(4): 923–931. Published online 2020 Aug 18. doi: 10.3906/kim-1912-
PMCID: PMC7751918 PMID: 33488202 The use of water-soluble phthalocyanines as textile
dyes in nylon/elastane fabric: fastness and antibacterial effectiveness Armağan GÜNSEL,1
Ayşe USLUOĞLU,1,2 Ahmet Turgut BİLGİÇLİ,1 TOSUN Büşra,1 Gülnur ARABACI,1 and
Meryem Nilüfer YARAŞIR*,1
Polymer Chemistry Issue 30, 2021 Design, synthesis and use of phthalocyanines as a new
class of visible-light photoinitiators for free-radical and cationic polymerizations
Louise Breloy,a Ozgur Yavuz, ORCID logo b Ismail Yilmaz, ORCID logo *b Yusuf Yagci
ORCID logo *b and Davy-Louis Versace ORCID logo
Journal of Porphyrins and PhthalocyaninesVol. 04, No. 04, pp. 432-437 (2000) Industrial
applications of phthalocyanines PETER GREGORY
7.Phthalocyanine and quinacridone pigments: Their history, properties and use
June 2005 Studies in Conservation 50(Supplement-1):19-29
DOI:10.1179/sic.2005.50.Supplement-1.19 Suzanne Lomax
Dandridge .A.G, Drescher .H.A, Thomas. J, GB Patent, 3221691928.
Linstead .R.P, J. Chem. Soc, (1934), 1022.
Kadish .K.M, Smith. K.M and Guilard .R ,(Eds.) The Porphyrin Handbook, Academic Press:
San Diego, (2003), Vol.15.
Leznoff .C.C, Lever .A.B.P, (Eds.) Phthalocyanines; Properties and Applications, VCH: New
York, (1993), Vol. 2.
Leznoff .C.C, Lever. A.B.P, and Bonnet. R, Chem. Chem. (1991), 30: 4453.
Boyle .R.W, Rousseu .J, Kudrevich .S.V, Ohochi .M.O.K and Lier .J.E, Br. J. Cancer, (1996)
,73, 49.
Eberhardt .W , and Hanack. M, Synthesis, (1997), 95.
Allied Chemical Corporation, Belg. Pat (1961),Chem. Abst. 1962, 57, 13784d.
Czech Pat 1984, Chem. Abst. (1984), 101, 153.
Kempa. A, and Dobrowlski. J, Can. J. Chem, (1988), 2553.
Tse .Y. H, Leznoff .C.C, and Lever .A.B.P, Inorg. Chem, (1991), 30, 4453.
Hanack .M. and Osio-Barcina. J, Synthesis, (1992), 211.
Nasser. S, Parisa .R, Jamaat Sadif .A, Shirvan, Samad .S, Amin. E, Maria .D and Ahmad .S,
Rapid and efficient synthesis of metallophthalocyanines in ionic liquid, J. Porphyrins
Phthalocyanines (2005), 9, 256-261.
Benson Getenga Ongarora; synthesis and characterization of water-soluble phthalocyanines
for diagnosis and treatment of cancer, degree of Doctor of Philosophy, Louisiana State
University and Agricultural and Mechanical College, December (2012).
Issam Ahmed Mohammed and Asniza Mustapha; Synthesis of New Azo Compounds Based
on N-(4-Hydroxypheneyl)maleimide and N-(4-Methylpheneyl) maleimide; Molecules —
Open Access Organic Chemistry Journal; 25 October 2010; 15.
Jan Milecki; LABORATORY OF ORGANIC CHEMISTRY; UAM, Poznań (2013).