Open Herald: Periodical of Methodical Research

Роль тканевого калликреина в нейропротекции и нейровоспалении у больных с изолированной черепно-мозговой травмой.

Кенжаев Л.Т

Ташкентская Медицинская Академия Кафедра анестезиологии и реаниматологии

Мухаммадова М.Б

Ташкентская Медицинская Академия Кафедра анестезиологии и реаниматологии

Keywords: ЗЧМТ, шкала GLASGOW, тканевой калликреин

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Abstract

Закрытая черепно-мозговая травма (ЧМТ) является довольно распространенным явлением и ежегодно поражает миллионы людей во всем мире. В структуре травм наиболее драматичной является черепно-мозовая травма. ЗЧМТ остаётся одной из наиболее важных проблем здравоохранения. Во всех странах мира наблюдается увеличение частоты случаев ЗЧМТ. Каллидиногеназа - калликреин ткани, компонент калликреин - кининовой системы (KKS), обладает защитным действием против ишемии мозга

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Восстановление сознания под влиянием каллидиногеназы наблюдалось быстро и

сокращало сроки пребывания больных в реанимационном отделении.

Использование Каллидиногеназы (тканевой калликрин) при изолированной ЗЧМТ

улучшает общее состояние больных и клинико-биохимические лабораторные данные.

Противовоспалительные цитокины в эффекте Калгена повышение приводит к

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